Textural Properties of Amoxicillin -Anionic Clays Composites for Possible Oral Diseases Uses

Hybrid nanostructures based on amoxicilin – hydrotalcite type anionic clays were synthesized by using coprecipitation and reconstruction of initial structure as synthesis methods. Scanning electron microscopy (SEM) technique and nitrogen adsorption-desorption isotherms was used to describe textural characteristics of the obtained hybrids. The plate let morphology defines the texture of the iron containing clay but these features changed to nonporous solid structures for the drug-clay hybrid materials. Results showed that these aggregated nanoparticles of layered double hydroxides or substituted ones could be good candidates as host for drug delivery systems with potential applications in dentistry. Texture of LDHs and intercalated compounds was studied to determine the way the guest molecules of amoxicillin were intercalated between hydrotalcite sheets.